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Add Metandienone Wikipedia

Darcy Rey 2025-09-27 13:24:45 +00:00
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Metandienone Wikipedia
<br>Electronegative atoms in a heteroaromatic ring withdraw electron density from the π‑system by inductive effect.<br>
Because the aromatic ring is now poorer in electrons, it becomes deactivated toward electrophilic attack – the σ‑complex that is formed during an EAS reaction is less stable.
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<br>The withdrawal of electron density also makes the positions on the ring that are directly attached to the heteroatom (or next to it) even poorer in electron density.<br>
Consequently, [https://www.valley.md/dianabol-cycle-benefits-and-risks](https://www.valley.md/dianabol-cycle-benefits-and-risks) the most favourable site for an electrophile is usually a position that is farther from the heteroatom – often the para‑like or meta‑like position relative to the heteroatom.<br>
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<br>In short: inductive withdrawal deactivates the ring and shifts the reactivity toward positions further away (often para) from the electron‑withdrawing heteroatom.
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